Mapping Tissue Optical Attenuation to Identify Cancer Using Optical Coherence Tomography
Identifieur interne : 006607 ( Main/Exploration ); précédent : 006606; suivant : 006608Mapping Tissue Optical Attenuation to Identify Cancer Using Optical Coherence Tomography
Auteurs : Robert A. Mclaughlin [Australie] ; Loretta Scolaro [Australie] ; Peter Robbins [Australie] ; Christobel Saunders [Australie] ; Steven L. Jacques [États-Unis] ; David D. Sampson [Australie]Source :
- Lecture Notes in Computer Science [ 0302-9743 ] ; 2009.
Abstract
Abstract: The lymphatic system is a common route for the spread of cancer and the identification of lymph node metastases is a key task during cancer surgery. This paper demonstrates the use of optical coherence tomography to construct parametric images of lymph nodes. It describes a method to automatically estimate the optical attenuation coefficient of tissue. By mapping the optical attenuation coefficient at each location in the scan, it is possible to construct a parametric image indicating variations in tissue type. The algorithm is applied to ex vivo samples of human axillary lymph nodes and validated against a histological gold standard. Results are shown illustrating the variation in optical properties between cancerous and healthy tissue.
Url:
DOI: 10.1007/978-3-642-04271-3_80
Affiliations:
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